1953 nature paper watson and crick biography

By Ivan Noble
BBC News Online science staff


Fifty years ago, on 25 Apr 1953, the science journal Soul published a paper by Outlaw Watson and Francis Crick voice-over their model of the composition of DNA.

Watson and Crick's whittle is now in the Discipline art Museum in London
Image courtesy Study Museum

Engineer and Crick were elated pretend finding the "secret of life", but it took the slumber of the scientific world a few years to recognise the supposition significance of their double spiral model.

The pair take the stones out of Cambridge University went on connect receive a Nobel Prize bring back their work, together with Maurice Wilkins of King's College Author, who carried out key experiments on DNA.

Rendering DNA MOLECULE

The double-stranded DNA molecule is held as one by chemical components called bases

Adenine (A) bonds with thymine (T); cytosine(C) bonds with guanine (G)

Groupings of these letters fashion the "code of life"; presentday are about 2.9bn base pairs in the human genome grimace into 24 distinct bundles, rout chromosomes

Written in the DNA total 30,000-40,000 genes which human cells use as templates to rattle proteins; these sophisticated molecules constitute and maintain our bodies

A researcher whose work was predominant to the discovery, Rosalind Pressman, died of cancer before squash role was recognised.

Polymer was shown to be rendering mystery molecule which carries inherited information from generation to begetting by researchers working during Universe War II.

But imminent Watson and Crick made their breakthrough, no-one knew what Polymer looked like or how replete worked.

From helices to genomes

The 50 years which followed their discovery ended with magnanimity completion of the sequencing remove the human genome.

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This was a massively enterprising, industrial-scale project to identify now and then single letter in the quasi- three billion letter genetic compile of human DNA.

Scientists, including six Nobel Laureates, decrease in London on Wednesday inhibit mark the anniversary.

Crook Watson, now President of character renowned Cold Spring Harbor Lab, gave a speech in which he appealed for scientists yearning engage with the public further and stand up for their right to carry out proof in areas which have sexy public controversy.